Darkest Dungeon 2 Plague Doctor Build Best Guide

Darkest Dungeon 2 Plague Doctor Build Best Guide

Plague Doctor Build

Darkest Dungeon 2 Plague Doctor Build Guide

The Plague Doctor is a popular character class in the Darkest Dungeon series, known for their expertise in alchemy and healing, as well as their ability to inflict devastating diseases upon enemies

In Darkest Dungeon 2, the Plague Doctor is a versatile support character who excels at both dealing damage over time and providing support to the party. They primarily rely on their alchemical concoctions and surgical tools to unleash deadly diseases upon enemies while also providing limited healing and utility to their allies.

Furthermore, the Plague Doctor has some utility skills to manipulate battle positions, allowing them to reposition themselves or other party members strategically. This can be useful for setting up optimal skill combinations or moving afflicted heroes out of harm’s way.


Darkest Dungeon 2 Plague Doctor Skills

Magnesium Rain
Noxious Blast
Battlefield Medicine
Indiscriminate Science

Darkest Dungeon 2 is one the hardest turn-based game ever made. Healing is the most important aspect of the game and healers are the soul of the game. You may need to heal all the time in the game before and just after every turn. But You need to find and build the best healer in the game.

The Plague Doctor is known for their expertise in alchemy and healing, as well as their ability to inflict devastating diseases upon enemies. Her first 3 skills in the above-mentioned table are Magnesium Rain, Incision, and Noxious Blast and these skills basically buff the DOT damage and inflict the enemies with different stages of damage over time. Her DOT is very high and can do almost every kind of Damage overtime available in the game.

Battlefield Medicine and Indiscriminate Science are the best healing skills available in the Drakest DUNGEON 2. She becomes an absolute beast with the combination of the above skills and nothing can stop this if you build a plague doctor.


Darkest Dungeon 2 Plague Doctor Best Path

In Darkest Dungeon 2, no path is available to any hero at the start of the game. But there will be an option to obtain a path once you invest in The Living City. You can consider a path like an upgrade for a character. There are basically 3 paths in the game for every hero and of course, each path has a different impact and outcome on the character, build and real progress of the unit.

Like all other units in the game, There are 3 unique paths available for Plague Doctor Build:-

Pict- Darkest Dungeon Fandom Wiki

As you can see in the above snapshot of all three available paths of Plague Doctor. All of them come with a negative impact as happens with every character’s patch so Doctor is no exception. Alchemists and Physicians are a very good path to make doctor a super solid unit but in this build, we are going to focus on Surgeon for more HP and never-ending healing from behind.


We can make a powerful Plague Doctor build with other paths Alchemist and Physician. I’m doing a bit of the testing right now and will post the outcome with other paths too soon.

Darkest Dungeon 2 Plague Doctor Trinkets

In Darkest Dungeon 2, Each hero has 3 Unique Trinkets exclusively available to them only like Paths. Each Trinket has a different impact and outcome on the character, build and real progress of the unit.

Pict- Darkest Dungeon Fandom Wiki

it seems Annotated Textbook is there in the game for The Plague Doctor Build. You can read the description in the above image that will provide 50% more healing if it’s equipped with Medicinal Herbs(Combat item- EXPLAINED IN NEXT PORTION).


You can avoid and ignore Early Experiment and Storage Room Key bcoz of their direct negative impact on the build. we can pick Indelible Protectorate, it has no condition and nothing negative for our Plague Doctor Build. It will provide a 20% bonus to healing. This Plague Build is going to create an invincible Plague Doctor.

Darkest Dungeon 2 Plague Doctor Combat items

There are various Combat items available in the market Dungeons 2. These combat items provide buffs, remove debuff from character, and help the team with different utilities like damage increase, healing and other support-oriented stuff. There is a long list of combat items with different consumable tags. we will provide an in-depth guide about combat items in Darkest DUNGEON 2.

For Plague Doctor, There are plenty of options available but I would stick this post for best in slot item and that is going to be Medicinal Herbs without any doubt.


Medicinal Herb is basically a debuff removal item which can be used 3 times in an encounter. but this plague doctor’s build does not need this ability at all. So, instead, we will use and optimize our build to combine Medicinal Herbs with Annotated Textbooks for more healing.

Pro Tip-: Still, You can use Herbs two times in a row and should save the last one for the next move to obtain a healing buff from herbs and textbook combo.

So, this is all about our The Plague Doctor Build Guide in darkest dungeon 2. If you are still looking for other Darket Dungeion 2 Guides, you can visit our Darkest Dungeon 2 category.


Don’t forget to drop your opinion in the comment section, You are always for any suggestions, feedback and critical criticism for better and the best information and guide on darkest dungeon 2.

Leave a Reply